Most of the articles published so far are case studies and
predominantly based on isolated cases. Although some contain diagnostic hypotheses, there is yet no consensus over the etiology, risk
factors, and epidemiology of this condition. A number of important studies have been conducted using anonymous questionnaires available
to the general public, via internet. Based on these questionnaires diagnoses have been made and conclusions drawn. None of those studies
utilized control groups for comparison.
There is a need for larger studies in order to better understand the clinical picture.
There is also a need for good diagnostic criteria. Otherwise many cases may remain unnoticed or misdiagnosed.
Read the following articles with a
large dose of skepticism...
Marcel Waldinger
ReGS in Males
Stronger Evidence for Small Fiber Sensory Neuropathy in Restless Genital Syndrome: Two Case Reports in Males.
Marcel Waldinger | November 2010 | Netherlands
New Insights into Restless Genital Syndrome
Static Mechanical Hyperesthesia and Neuropathy of the Nervus Dorsalis Clitoridis.
Marcel Waldinger | November 2009 | Netherlands
Restless Genital Syndrome
Before and After Clitoridectomy for Spontaneous Orgasms: A Case Report.
Marcel Waldinger | November 2009 | Netherlands
PGAD: An Update of Theory and Practice
A perplexing condition characterized by high levels of genital arousal occurring in the
absence of subjective sexual interest or desire.
Sandra Leiblum | 2009 | USA
Genital Arousal in women
[page 14] Spontane, intrusive and unwanted genital arousal (e.g. tingling, throbbing, pulsating)
in the absence of sexual interest and desire.
Sandra Leiblum | 2007 | presentation congress Australia
Persistent Sexual Arousal Syndrome: A Descriptive Study
This study is very controversial and is not supported by women suffering from PGAD/ReGS! [Anonymous questionnaires available to the general public, via internet]
JSM | 2005 | USA
Update previous article
This study is very controversial and is not supported by women suffering from PGAD/ReGS! [Anonymous questionnaires available to the general public, via internet]
JSM | 2006 | USA
PSAS
A Newly Discovered Pattern of Excessive Female Arousal That Can Continue Unremittingly for Hours, Days, or Weeks.
Sandra Leiblum | 2001 | USA
Persistent Genital Arousal Disorder (PGAD)
A Case Report in a Woman with Lifelong PGAD Where Serendipitous Administration of Varenicline Tartrate Resulted in Symptomatic Improvement.
Irwin Goldstein| 2009 | USA
Persistent Genital Arousal Disorder
Associated with functional hyperconnectivity of an epileptic focus.
Department of Oncology and Neuroscience | 2010 | Italy
PGAD Perspectives
Insights and Perspectives.
Sherlock | 2010 | Australia
Case report
Physical Therapy Treatment of Persistent Genital Arousal Disorder During Pregnancy.
Talli Yehuda Rosenbaum | 2009 | Israël
A Case report:
Pelvic Congestion Syndrome Presenting as Persistent Genital Arousal
Katie Thorne, MBBS, and Bronwyn Stuckey, FRACP - Keogh Institute for Medical Research | 2007 | Australia
Case report
Persistent sexual arousal a woman with associated cardiac defects and raised atrial natriuretic peptide.
The Jane Wadsworth Clinic - St Mary’s Hospital | 2007 | London UK