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You are here:  Home   What doctors should know    Sources/Articles                                                                                                     Last Update: 5 oct - 2015



 Articles Marcel Waldinger

 Articles Sandra Leiblum

 Articles Barry Komisaruk

 Articles Irwin Goldstein

 Other articles



Most of the articles published so far are case studies and predominantly based on isolated cases. Although some contain diagnostic hypotheses, there is yet no consensus over the etiology, risk factors, and epidemiology of this condition. A number of important studies have been conducted using anonymous questionnaires available to the general public, via internet. Based on these questionnaires diagnoses have been made and conclusions drawn. None of those studies utilized control groups for comparison.

There is a need for larger studies in order to better understand the clinical picture. There is also a need for good diagnostic criteria. Otherwise many cases may remain unnoticed or misdiagnosed.

Read the following articles with a large dose of skepticism...
Marcel Waldinger

ReGS in Males
Stronger Evidence for Small Fiber Sensory Neuropathy in Restless Genital Syndrome: Two Case Reports in Males.
Marcel Waldinger | November 2010 | Netherlands

New Insights into Restless Genital Syndrome
Static Mechanical Hyperesthesia and Neuropathy of the Nervus Dorsalis Clitoridis.
Marcel Waldinger | November 2009 | Netherlands

Restless Genital Syndrome
Before and After Clitoridectomy for Spontaneous Orgasms: A Case Report.
Marcel Waldinger | November 2009 | Netherlands

Successful Transcutaneous Electrical Nerve Stimulation
in Two Women with Restless Genital Syndrome: The Role of Ad- and C-Nerve Fibers.
Marcel Waldinger | November 2009 | Netherlands

Persistent Genital Arousal Disorder in 18 Dutch Women: Part I
MRI, EEG, and Transvaginal Ultrasonography Investigations.
Marcel Waldinger | November 2008 | Netherlands

Persistent Genital Arousal Disorder in 18 Dutch Women: Part II
A Syndrome Clustered with Restless Legs and Overactive Bladder.
Marcel Waldinger | November 2008 | Netherlands

Sandra Leiblum

PGAD: An Update of Theory and Practice
A perplexing condition characterized by high levels of genital arousal occurring in the absence of subjective sexual interest or desire.
Sandra Leiblum | 2009 | USA

Genital Arousal in women
[page 14] Spontane, intrusive and unwanted genital arousal (e.g. tingling, throbbing, pulsating) in the absence of sexual interest and desire.
Sandra Leiblum | 2007 | presentation congress Australia

Persistent Sexual Arousal Syndrome: A Descriptive Study
This study is very controversial and is not supported by women suffering from PGAD/ReGS! [Anonymous questionnaires available to the general public, via internet]
JSM | 2005 | USA

Update previous article
This study is very controversial and is not supported by women suffering from PGAD/ReGS! [Anonymous questionnaires available to the general public, via internet]
JSM | 2006 | USA

A Newly Discovered Pattern of Excessive Female Arousal That Can Continue Unremittingly for Hours, Days, or Weeks.
Sandra Leiblum | 2001 | USA

Barry Komisaruk

Persistent Genital Arousal Disorder (PGAD)
Prevalence of sacral spinal (Tarlov) cysts
in Persistent Genital Arousal Disorder
Barry Komisaruk | 2012 | USA

Irwin Goldstein

Persistent Genital Arousal Disorder (PGAD)
A Case Report in a Woman with Lifelong PGAD Where Serendipitous Administration of Varenicline Tartrate Resulted in Symptomatic Improvement.
Irwin Goldstein | 2009 | USA

Persistent Genital Arousal Disorder (PGAD)
Case Report of Long-Term Symptomatic Management with Electroconvulsive Therapy
Irwin Goldstein | 2009 | USA

Other articles

A New Medical Treatment With Botulinum Toxin in Persistent Genital Arousal Disorder:
Successful Treatment of Two Cases
Hakan Nazik, Murat Api, Hakan Aytan and Raziye Narin|
2014 |Turkey

Restless Genital Syndrome in Parkinson Disease
Case Report
Camila C. Aquino,MD, MSc; TiagoMestre,MD, MSc;
Anthony E. Lang, MD, FRCPC |2014 |Canada

A Periclitoral Mass as a Cause of Persistent Genital Arousal Disorder
Case Report
JSM |2014 |USA

If you have persistent genital arousal disorder (PGAD) you are not alone.
This is a special newsletter for patients who have PGAD and for professionals who treat them.
Newsletter Pudendal Hope | June 2013 |
( pudendalhope.info)

A Report of Three Cases.
Persistent Genital Arousal Disorder Misdiagnosed Because of Islamic Religious Bathing Rituals.
Ejder Akgun Yildirim , Munevver Hacioglu , Altan Essizoglu, Ilker Kucukparlak | Aug. 2012 |Turkey

Persistent Genital Arousal Disorder
Successful Treatment with Duloxetine and Pregabalin in Two Cases
Philippsohn and Tillmann | Nov. 2011 | Germany

Mogelijk verborgen hernia(s)
In Women, Hernias May Be Hidden Agony
The New York Times | May 2011 | USA

Persistent Genital Arousal Disorder
Associated with functional hyperconnectivity of an epileptic focus.
Department of Oncology and Neuroscience | 2010 | Italy

PGAD Perspectives
Insights and Perspectives.
Sherlock | 2010 | Australia

Case report
Physical Therapy Treatment of Persistent Genital Arousal Disorder During Pregnancy.
Talli Yehuda Rosenbaum | 2009 | IsraŽl

Persistent Genital Arousal Disorder (PGAD)
A review of the literature and recommendations for management.
David Goldmeier | 2009 | UK

A Case report:
Pelvic Congestion Syndrome Presenting as Persistent Genital Arousal
Katie Thorne, MBBS, and Bronwyn Stuckey, FRACP - Keogh Institute for Medical Research | 2007 | Australia

Case report
Persistent sexual arousal a woman with associated cardiac defects and raised atrial natriuretic peptide.
The Jane Wadsworth Clinic - St Maryís Hospital | 2007 | London UK

Possible Etiologies and Potential Therapies
H.Randall Craig, M.D. | 2006 | USA

Relatie met SSRI's
Persistent genital arousal in women a new syndrome entity.
Leiblum/Goldmeier | 2006 | UK - USA

Persistent Sexual Arousal Syndrome
Associated with Increased Soy Intake
Alison Amsterdam, M.D.| 2005 | USA

Case reports and much more...
Among others: Solutions suggested by women to minimize symptoms.
Womenís Sexual Health Journal | 2005 | USA




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